Generations of progress have led to this moment in Huntington’s disease

Building upon past research, we’re working to redefine the future of Huntington’s disease (HD) care today. Partnering with the HD community, we're actively studying the cause of HD – the mutant huntingtin (mHTT) protein – so we can better understand its role in disease progression.4,5 By targeting the fundamental cause of the disease, researchers are exploring how to potentially slow or stop the progression of this devastating disease, to offer hope to individuals with HD.

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Get reacquainted with HD

Huntington’s disease is a rare, genetic, neurodegenerative disease.5 It is ultimately fatal and has a devastating impact on patients and entire families across generations.6,7

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Discover the role of mHTT

Current evidence indicates that HD pathology is caused by the production of a mutant form of huntingtin (mHTT) protein due to a cytosine–adenine–guanine (CAG) trinucleotide repeat expansion in the gene encoding huntingtin.5

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Explore new frontiers in HD

Learn about the ongoing research areas aiming to offer hope to individuals with HD.

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